Granulocytes are leukocytes that have a specific granular( granular) cytoplasm. The bone marrow is responsible for their production. Agranulocytosis - an ailment that is characterized by a decrease in the content of granulocytes in the blood. This leads to an increase in the susceptibility of the patient to various fungal and bacterial diseases. Human immunity is gradually weakening, which is fraught with the development of various complications in the future. But with the timely detection of pathology and its competent treatment, all this can be avoided.
According to statistics, it is women who are more likely to suffer an ailment( 2-3 times more often than men).There is a disease usually after reaching 40 years. Agranulocytosis has a rather high lethality, which reaches 80%.
Agranulocytosis of the hapten type appears due to the influence of diamox, barbiturates, insecticides and other chemicals. Th
Depending on the time of onset, agranulocytosis happens:
There is another classification of agranulocytosis, which is used in medical institutions:
The causes of agranulocytosis are quite diverse. Even the administration of certain medications may provoke the progression of pathology. Particularly it is worth highlighting the following factors that contribute to the development of the disease:
Agranulocytosis is manifested by the following symptoms:
Symptoms of the disease differ depending on the type of ailment and the state of the patient's health. In some cases, they can be expressed very clearly, while in others they can be practically absent. It is very important to notice the manifestation of the first symptoms of a disease in a timely manner so that you can seek medical help as soon as possible.
Myelotoxic disease may have the following complications:
If the disease is caused by haptens or arises from the weakness of immunity, the symptomatology of the disease manifests itself most vividly. Among the sources that cause infection, saprophyte flora is singled out, which includes the Pseudomonas aeruginosa or Escherichia coli. In this case, the patient has a strong intoxication, raising the temperature to 40-41 degrees. Pseudomonas aeruginosa can cause metastatic infectious ulcers on the body, which can be found on the surface of the kidneys, lungs, or other organs during autopsy.
In a potential risk group, patients who had previously been exposed to radiation, suffered severe infectious diseases, or underwent prolonged therapy with medication.
Every person who has one or more of the symptoms listed above is required to take an X-ray of the lungs, to examine their blood for sterility and to pass a biochemical blood test. Also, a doctor can prescribe a consultation with an otolaryngologist or even a dentist. It is important to distinguish agranulocytosis from anemia, leukemia or HIV.
disease Agranulocytosis should be treated in several stages:
The prognosis of the treatment of the disease is usually favorable. It can worsen the appearance of foci of tissue necrosis and infectious ulcers.
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If you think that you have Agranulocytosis and symptoms typical for this disease, then you can help doctors: an allergist, an immunologist, a hematologist.
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