Tablets imovan : instruction manual , reviews, price , analogs

Category Medicine | August 12, 2017 17:55

Composition The active ingredient of the drug - zopiclone .Additional components: wheat starch, lactose, magnesium stearate, dicalcium phosphate dihydrate, sodium starch, hypromellose, titanium dioxide, polyethylene glycol.

Product form

medicine sold in tablets.

Pharmacological action

Hypnotic.

Pharmacodynamics and pharmacokinetics

drug belongs to tsiklopirrolonam .This hypnotic drug.It acts as an agonist of a particular receptors.The drug prolongs sleep, reduce the frequency of nighttime awakenings, quality of sleep improves.

drug is rapidly absorbed .Hours, gender and number of receptions of the absorption is not affected.The maximum concentration is reached after 90-120 minutes.

Bioavailability - 80%.

drug is rapidly distributed from the vascular .The degree of connection with plasma proteins - about 45%.

Reduced plasma concentrations in the range 3.75 -15 mg doses not dose-dependent.The half-life time of about 5 hours.

imovan metabolized in the liver to produce metabolites : N-oxide and N-demethylated derivative .Write mainly in the form of metabolites .Approximately 80% - kidney, about 16% - in the feces.

Indications

medicine used in situational, chronic and transient insomnia adult aged patients.

Contraindications Do not use the drug in case of hypersensitivity to its components, the age of 15 and decompensated respiratory failure .

Side effects

Adverse reactions have individual character, they are dependent on the dosage and individual sensitivity to the drug person.Most often, there is a bitter taste in the mouth as a side effect.In addition, you may experience the following reactions:

  • CCC - palpitations;
  • systemic effects - muscular hypotonia, chills, sweating , asthenia , fatigue;
  • organs of vision - diplopia , amblyopia ;
  • GIT - coated tongue, dyspepsia , dry mouth, diarrhea , anorexia , bad breath, nausea, vomiting, constipation , increased appetite;
  • metabolism - weight reduction;
  • skin - skin rash, sweating, toxic epidermal necrolysis , itching , Stevens-Johnson , erythema multiforme .In the event of data taking the drug symptoms should stop;
  • immune system - urticaria , anaphylactic reaction , angioedema ;
  • respiratory system - dyspnea , shortness ;
  • musculoskeletal system - heaviness in the limbs, muscle weakness.

In laboratory tests, in rare cases, there may be increased levels of transaminases and / or levels of alkaline phosphatase .

In rare cases, the reported seizures.

patients in the elderly may appear palpitations, anorexia , excited state, tremor , vomiting, sialoreya , a sense of anxiety.

cases of anger and behavioral disorders, which are caused by amnesia recorded in clinical studies.

After discontinuation of the drug may rebound insomnia , anxiety, sweating, confusion, palpitations, delirium , irritability, muscle pain, tremor , agitation , headachepain , tachycardia , nightmares.In severe cases may appear derealization , hyperacusis , hypersensitivity, depersonalization, numbness or tingling in the extremities, hallucinations .

for use imovan Guide (Method and Dosage)

course the use of the drug as possible to be short-lived.Instructions on imovan recommends to take it just before bedtime.Treatment situational insomnia lasts 2-5 days, when temporary insomnia - 2-3 weeks.When chronic insomnia course duration is determined individually.

for use imovan Guide reports the following dosages:

  • patients up to 65 years - 7.5 mg per day;
  • from 65 patients - the initial dosage of 3.75 mg per day, which increases in case of need.

If there are problems with the work of the liver and respiratory failure dose - 3.75 mg per day.

Overdose

Use of the drug in high doses can be life threatening, especially with simultaneous use of several CNS depressants (including alcohol).

Main symptoms of overdose - CNS depression, which causes drowsiness or who .With a small overdose can be confusion or lethargy.High dosages can cause ataxia , hypotension , respiratory depression, hypotonia , methemoglobinemia , and sometimes fatal.

If less than 60 minutes after the overdose, the patient can cause vomiting, in other cases, a gastric lavage.Also useful is reception of activated carbon, to reduce the degree of absorption of the drug.

It is advisable to observe the work of the heart and respiratory systems.It can help administering flumazenil .

Hemodialysis not advisable, as the drug active ingredient is characterized by a large volume of distribution.

Interaction

can not be taken in combination with Imovanom drugs that have a depressant effect on the nervous system, namely derivatives morphine , sedatives , antipsychotics , barbiturates , tranquilizers , Clonidine and so on. The reception at the same time clozapine increases the probability of respiratory failure and cardiac activity.In addition, during the course of treatment can not drink alcohol and alcohol-containing means.Combining imovan and Erythromycin causes uncontrolled increase in steps zopiclone .

Conditions of Sale

Vacation imovan of pharmacies is made according to the recipe.The drug is assigned a specialist.Buy this tool can not be without a prescription.

Storage

Store means you need at a temperature up to 25 ° C in a dry place out of reach of children.

Shelf life

three years.

Analogs imovan

Matches code ATC 4th level:
  • Relakson
  • Ivadal
  • Sanval
  • Zolpidem
  • Somnol
  • Andante
  • Zopiclone

Analogs imovan in pharmacies are manufactured following:

  • Zopiclone;
  • Zopiclone-WN;
  • Normason;
  • Piklon;
  • Somnol;
  • Sonnat;
  • Sonovan.

Reviews on imovan

reviews Imovane forums show the effectiveness of the medication.Patients report that the drug has a positive effect in short courses.The effect of the drug will quickly notice is not addictive.

Reviews on imovan about the side effects reported rarely.Patients say the iron taste and a sense of bitterness in the mouth.There are cases where after the drug appear nightmares.

Price imovan where to buy

Often on the forums are wondering where to buy imovan in Moscow, St. Petersburg and other Russian cities.It means you can get in the pharmacy network on prescription, but in any online pharmacy you can not find it, as it is released only in the appointment of a specialist.

buy over the counter medications can cost about 270 rubles.In some cities imovan price may be lower, for example, 260 rubles.In Ukraine, it means more expensive.Imovan average price - about 100 hryvnia.

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