Acyclovir cream : instructions for use , price, reviews , analogs Acyclovir cream

Category Medications | August 12, 2017 17:59

Contents:

  • Acyclovir cream instructions for use
    • Product form and composition
    • Pharmacological action
    • Indications
    • Contraindications
    • Dosage
    • Side effects
    • Cautions
    • Overdose
    • Analogs
    • terms and conditions of storage
    • Cream Acyclovir price

Cream Acyclovir is an antiviral agent for external use.It has a therapeutic effect in various herpes infections by blocking virus replication.

release form and composition

Cream Acyclovir for external use is available in tubes of 5 g The active ingredient of the drug is acyclovir, its concentration - 5% (1 g of ointment contains 5 mg of acyclovir).In addition to the active ingredient cream contains auxiliary components, which include:

  • Medical mineral oil.
  • emulsifying cetostearyl alcohol type A.
  • poloxamer 407.
  • Propylene glycol.
  • Dimethicone.
  • Purified water.

in a cardboard bundle product contains 1 tube with 5 g of cream and its instruction manual.The concentration of the active substance is sufficient to block virus replication.

Pharmacological action

The active ingredient of the drug acyclovir is a nucleoside analogue of thymidine.Its mechanism of action is that, after penetration into the infected cell, the viral enzyme thymidine kinase catalyzes the conversion of acyclovir into acyclovir triphosphate, which is embedded in the viral genetic material (DNA) and prevents reading of information (transcription), which leads to blocking transcription process (formation andassembly of new viral particles).In healthy non-infected cells, virus, thymidine kinase enzyme is not present, therefore not converted into acyclovir triphosphate form and does not adversely affect the genetic material of cells.The most active virus manifests against the herpes virus (Herpes simplex) and shingles (Varicella zoster).Less impact effect of the drug substance has on cytomegalovirus and Epstein-Barr virus.

For external use, the active ingredient Acyclovir cream is well adsorbed by the skin cells and mucous membranes in the field of its application.In the systemic circulation acyclovir is practically not absorbed.

Indications

Acyclovir Cream is indicated for the treatment of cutaneous manifestations of various herpes infections, which include:

  • Herpes with rashes on the skin around the lips, genitals and other body parts.
  • Shingles with the development of characteristic rash on the skin of the appropriate innervation of the affected nerve by a viral infection.After applying the cream Acyclovir, the severity of the rash and pain intensity reduced.
  • Chickenpox - infectious viral process with the appearance of a rash all over the body in the form of small bubbles filled with fluid.

Not recommended Acyclovir cream application to the mucous membranes of the body.

Contraindications

use Acyclovir cream is contraindicated in case of individual intolerance to the main active ingredient of the drug or its auxiliary components.Also not recommended to apply the cream in the presence of allergic reactions, which mainly manifest changes on the skin in the form of appearance of the rash, itching or her development of a rash on the skin puffiness background that resembles a sting (urticaria).

Dosage

Cream Acyclovir is a drug for external use.It is applied to the affected area of ​​skin on which there are elements of the rash, indicating the presence of herpes infection.Also possible to apply the drug in the mouth and genital herpes.Multiplicity applying the cream - 5 times per day, with an interval between the application of a 4 hour.Duration of treatment is an average of 5 days.If during this time improving skin condition, amelioration of severity, and the rash has not occurred, then the extension of treatment is allowed up to 10 days.

Side effects

Cream Acyclovir generally well tolerated, this is due to lack of income of the active ingredient into the systemic circulation.Perhaps the development of allergic skin reactions after application of cream on it, which manifest themselves in the form of erythema (redness), rash, itching or hives.In rare cases may develop angioedema angioedema (severe swelling of the skin and subcutaneous tissue, preferentially localized on the face and genitals).In case of side effects, the use of the drug should be discontinued.

Cautions

Before using acyclovir cream, you need to read the instructions for use, which is embedded in a cardboard box.It is important to pay attention to such specific instructions:

  • can not use acyclovir cream for the treatment of herpes infections of the eye (keratitis), for this purpose there is a special formulation of the drug - eye ointment.
  • the absence of effective treatment should consult a doctor or dermatologist infectious diseases to address the issue of the use of antivirals for systemic effects (reception in the form of tablets).
  • allowed to use acyclovir cream for pregnant women and breast-feeding as the active ingredient of the drug is not absorbed into the systemic circulation.

The pharmacy network cream Acyclovir without prescription.In case of any questions or doubts, it is desirable to consult a doctor.During treatment of herpes of the lips you need to follow recommendations for preventing infection with this infection of healthy people (individual utensils and personal care products).

Overdose Due to the fact that the active ingredient of the drug is not absorbed into the systemic circulation, cases of overdose are unknown.Sometimes substantial deposition on the skin may develop side effects in the form of erythema and allergic reactions.

Analogs

similar medicines that contain the same active substance, are - Atsiklostad, Vivoraks, gerpevir, Gerperaks, Zovirax.

Terms and conditions of storage

Shelf-life of the drug from the time of its production is 2 years.After the printing of packaging and the use of ointments, its shelf life is 30 days.Keep Acyclovir cream must be in the dark, place inaccessible to children with an air temperature + 15-25 ° C.

Cream Acyclovir price

Acyclovir cream for local and external application of 5%;aluminum tube 5 g - 27 rubles.