Aertal : instructions for use , price, reviews , analogs Aertal tablets

Category Medications | August 12, 2017 17:59


  • Aertal pills instructions for use
    • Product form and composition
    • Pharmacological action
    • Indications
    • Contraindications
    • Dosage
    • Side effects
    • Cautions
    • Overdose
    • Aertal analogues
    • terms and conditions of storage
    • Aertal price

Aertal tablets are non-steroidal anti-inflammatory drugs.They are used as an anesthetic agent in various inflammatory, degenerative diseases of the organs and structures of the musculoskeletal system.

release form and composition

Aertal Tablets are available in dosage form - film-coated tablets.Their rounded shape, the color is white.The main active substance is aceclofenac, which is contained in an amount of 100 mg per 1 tablet.Also, it includes a number of auxiliary compounds which include:

  • glycerol distearate.
  • Croscarmellose sodium.
  • Povidone.
  • microcrystalline cellulose.
  • sepifilm casing 752 is white (hypromellose, microcrystalline cellulose, titanium dioxide (E 171), macrogol stearate).

Packaging tablets in blister packs made of 10 pi

eces.A carton may contain 1,2,4, 6 and 9 of the blisters with the corresponding total number of tablets.

Pharmacological action

atseklofenak The active substance of the drug is a non-steroidal anti-inflammatory and anti-rheumatic agent.The mechanism of action of the active substance is to decrease the synthesis of prostaglandins, which are the main mediators of inflammation.They are synthesized by cells of the immune system is damaged structures of the locomotor system and have such biological effects, which are the basis of the inflammatory response:

  • hyperemia - increased blood flow to the area of ​​inflammation due to the impact of prostaglandins on the venules with their contraction.
  • tissue edema - prostaglandins increase the permeability of microvascular wall, which leads to the output of liquid blood (plasma) in the field of intercellular substance inflammatory response.
  • Pain - appears by direct stimulation of sensory nerve endings prostaglandins and their mechanical compression of tissue edema.

synthesis of prostaglandins in the area comes from the predecessor - arachidonic acid.Aceclofenac blocks the enzyme cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid to prostaglandins active.In this Aertal pills help reduce the concentration of prostaglandins and the severity of the inflammatory response and pain.

After receiving tablets Aertal inside aceclofenac absorbed into the bloodstream from the intestine, its therapeutic concentration is reached after 30 minutes, the maximum concentration - 1.5-3 hours.The active ingredient of the drug is distributed throughout the body.The larger the number is stored in the synovial fluid, cartilage and connective tissue.To a lesser extent aceclofenac penetrates the central nervous system structures of the blood-brain barrier.Also, it can pass through the placenta into the body of the developing fetus during pregnancy and in breast milk during lactation.Active substance from the body the drug is excreted mainly in urine in the kidney after partial processing in the liver.The half-life (the time of removing 50% of the dose) was 4 h.


use tablets Aertal shown in a number of diseases of the structures of the musculoskeletal system, accompanied by the development of the inflammatory response and pain, these include:

  • Rheumatoid arthritis - an autoimmune pathology, in which the produced antibodies against tissue and structuresjoints.Thus there is a deterioration of the inflammatory response within the joint.
  • Arthritis - inflammation of joint tissues caused by infection (usually bacteria) or local hypothermia.
  • Osteoarthritis - inflammatory response, which evolved in the joint due to degenerative processes in the cartilage it to their destruction.
  • osteochondrosis - Pathology of the spine as a result of destruction of cartilage intervertebral discs.It may be accompanied by the development of the protrusion (protrusion without breaking the shell) or disc herniation (the formation of hernia sac with damage to the peripheral fibrous shell disc).
  • Periarthritis - inflammation in the periarticular tissues and ligaments.
  • as analgesic Aertal tablets may be used for dental pain, dysmenorrhoea (painful menstruation), muscle or back pain after excessive physical exertion.

Overall Aertal pills used in the treatment of inflammatory diseases of the musculoskeletal system as a symptomatic treatment to reduce the severity of inflammation and pain intensity.


tablets Reception Aertal contraindicated in a number of pathological and physiological states of the body, which include:

  • presence of gastric or duodenal ulcer with high risk of bleeding from it - in this case, aceclofenac can cause deteriorationdevelopment of bleeding by blocking the synthesis of prostaglandins in the stomach necessary to protect its mucosa from the damaging effect of hydrochloric acid gastric juice.
  • presence of gastrointestinal bleeding in the past, especially provoked by taking any non-steroidal anti-inflammatory drugs.
  • clotting disorder - the active ingredient of the drug reduces blood clotting and in this case may lead to the development of internal or external bleeding.
  • Hepatic or renal insufficiency, in which disrupted the process of removing the active substance from the body.
  • decompensated heart failure with marked deterioration of the pumping function of the heart.
  • Idiosyncrasy aceclofenac or excipients.
  • Allergic reactions to components of the drug, which may be accompanied by the development of an asthmatic condition (narrowing of the bronchi with the development of shortness of breath), allergic rhinitis (inflammatory reaction of the nasal mucosa on NSAIDs), rash on the skin with her or without swelling it.
  • early pregnancy (there is a risk of developing heart disease in the fetus), breastfeeding (reliable data about the dangers of the drug is not present, since the active ingredient is in low concentration in milk, however, it is recommended to refrain from taking the medication).
  • Acceptance of the drug to children under 18 years is contraindicated.

Determining whether contraindications to the use of the drug must be conducted before the start of its application.


Aertal tablets taken as a whole, without chewing.Upon receipt of a sufficient amount of water is drunk.It is desirable to hold the reception after the meal, on an empty stomach because of their negative effect on the mucous membrane of the stomach or duodenum may be enhanced.The maximum daily dose is 200 mg (2 tablets in 2 divided doses at regular intervals).The need to reduce the dose for elderly patients is not, but it is necessary to carefully monitor the functional state of the liver and kidneys.With caution used drug for people with a pathological process in the liver or kidneys.The recommended course of treatment is not more than 5 days.In general, the smaller the treatment, the less risk of side effects or complications from the drug.

Side effects

In connection with the partial suppression of the synthesis of prostaglandins necessary for the normal course of a number of physiological processes in the body, pills Aertal may lead to the development of side effects of various organs and systems:

  • digestive system - nausea, vomiting, epigastric pain with (upper abdomen), or over the entire surface of the abdomen of spastic character (sometimes the pain can occur in the form of cramps), bloating (flatulence), unstable stool (constipation, diarrhea can be replaced and vice versa).In rare cases, or when used incorrectly (on an empty stomach and a long period of time) may develop gastrointestinal bleeding, ulcer perforation (forming of a through hole in the wall of the stomach or duodenal ulcer in the process), pancreatitis (acute inflammation of the pancreas).
  • Nervous system - insomnia, headache, intermittent dizziness.Less possible disorientation in space and time, expressed excitement, visual impairment, hearing, perception of taste, tinnitus, tremor (shaking) hands, spasms of varying severity.
  • kidneys - hematuria (blood in urine), at least the development of interstitial nephritis (inflammation) and renal failure.
  • liver - increase in liver enzymes transaminases (ALT, AST), which indicates the destruction of the hepatocytes (liver cells).
  • Red bone marrow and blood formation system - leukopenia (reduction in the number of white blood cells in the blood), hemolytic or aplastic anemia (a decrease in red blood cell count and hemoglobin level in the blood), thrombocytopenia (decreased number of platelets in the blood to the development of increased bleeding from small blood vessels).
  • Cardiovascular system - tachycardia (rapid heart rate), increased systemic blood pressure (hypertension), heart failure.
  • Allergic reactions - depending on the severity of such a reaction may develop a skin rash, her pruritus, urticaria (a characteristic rash and swelling in the form of burning nettles), angioneurotic angioedema (pronounced swelling of the skin and subcutaneous tissue with predominant localization in the face and the outergenitals).Severe allergic reactions are accompanied by bronchospasm and status asthmaticus (narrowing of the bronchi with shortness of breath), the development of anaphylactic shock (multiple organ failure due to lower blood pressure with impaired consciousness).

In the event of one or more manifestations of the side effects, the drug should immediately stop and seek medical attention.


Aertal Before taking the tablets, you should carefully read the instructions.It is important to pay attention to a number of specific instructions on their use:

  • With long-term use of the drug periodic laboratory monitoring of hepatic function should be carried out, kidneys and peripheral blood.
  • With extreme caution drug used for people with kidney disease, liver, stomach, and duodenum.
  • Aertal combined use of tablets with other nonsteroidal anti-inflammatory drugs and hormones group of corticosteroids may increase the risk of side effects.
  • joint use of the drug and potassium-sparing diuretics can lead to increased levels of potassium ions in the blood (giperkaliyemiya).
  • To reduce the risk of reactions in the gastrointestinal tract in the form of erosion, ulceration, and bleeding from these, it is desirable to use the drug in a small concentration and a minimum rate.
  • During treatment tablets Aertal desirable to abandon the activities related to the necessity of high concentration and speed of psychomotor reactions.

drug in pharmacies on medical prescription.In case of any doubts or questions regarding his admission, consult with your doctor.

Overdose In case of excess of the therapeutic dose of the drug Aertal develop symptoms characteristic of its side effects.In this case, stop taking the tablets, in the hospital carried out a gastric lavage, intestines, and symptomatic therapy.No specific antidote.

Aertal analogues

analogs tablets Aertal mechanism of action is the main active ingredient - Lucidril, Tronak, Zerodol, Asefi.

Terms and conditions of storage

Aertal shelf life from date of manufacture of tablets is 4 years.Keep necessary in the dark, place inaccessible to children at an air temperature not higher than + 25 ° C

Aertal price

Aertal tablets, film-coated 100 mg, 20 pcs.- From 310 rubles.